Assistant Professor of Medical Chemistry – Biochemistry

Tel. 2140 685580

e-mail: tsideri@uth.gr

N6_methyladenosine (m6A) is the most prevalent RNA modification that controls all stages of mRNA life. m6A is essential for embryonic development, DNA damage response and other processes but often later in life acts as an “oncogene” to promote cancer cell survival. Additionally, often tumours are hypoxic and the response to hypoxia is also known to promote tumorigenesis. Our work focuses on understanding how m6A regulates the response to hypoxia in cancer cells and non-cancer context. We are focusing οn mRNA export and decay, translation and splicing. We aim to understand the fine tuning between the response to hypoxia and m6A in cancer and further to examine their combinatorial inhibition in abolishing cancer cell proliferation.

CV

Full list of Publications

https://pubmed.ncbi.nlm.nih.gov/?sort=date&term=Sideri+T&cauthor_id=38886580